As my anti-virus is real-time protected, so I seldom scan my compute manually unless there's a real-time error or any problem occur within my system. However, I will scan my computer manually once a month, i suppose.

Anyway, I will view regedit almost twice a week to check out any weird registry is entered my computer. So, if i found something weird, I might delete it in case if it's a virus/worm/spyware which changing ur computer's registry. Nowadays, lots of worms/viruses will disable the regedit from being edit. An error will appear which sound like "the regedit has been disabled by administrator.." But there's way to enable it back, if you're good enough then u can clear your computer from any virus and worms within the regedit.

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